Christiane Nusslein-Volhard Facts

Christiane Nusslein-Volhard Facts
Christiane Nusslein-Volhard (October 20, 1942 to present) is a German scientist known for her work on embryonic development. Her goal was to identify genes involved in the development of Drosophila melanogaster or fruit fly embryos.
Interesting Christiane Nusslein-Volhard Facts:
In the late 1970s and early 1980s, very little was known about the genetic and molecular mechanisms by which multicellular organisms develop from single cells to complex forms during embryogenesis.
Nüsslein-Volhard and Wieschaus identified genes used in embryonic development with a series of genetic screens. They created random mutations in fruit flies using EMS. Some of the mutations affected genes involved in the development of the embryo.
In normal Drosophila, each segment makes bristles called denticles in a band arranged on the side of the close to the head.
Many of these genes were given descriptive names based on the appearance of the mutant larvae, such as hedgehog.
Later, researchers identified exactly which gene had been affected by each mutation, thereby identifying a set of genes crucial for Drosophila embryogenesis.
She is known for working with fruit flies.
Nusslein-Volhard and Wieschaus were able to figure out that particular genes were involved in different processes during development based on the different mutant phenotypes.
They used fruit flies because there are a lot of them and because they reproduce very quickly. Many scientists for a very long time have used fruit flies for their experiments.
These experiments also greatly increased our understanding of the purpose of transcription, as well as what happens to cells during development.
She won the Nobel Prize in Physiology or Medicine in 1995, together with Eric Wieschaus and Edward B. Lewis, for their research on the genetic control of embryonic development.
Their research has greatly affected the Drosophila species and its development.
Due to the technology available at the time, the experiments were a very big deal it was considered a large scale experiment.
Nüsslein-Volhard is associated with the discovery of Toll, which led to the identification of toll-like receptors.
Nusslein-Volhard created a company that provides childcare for young German scientists.
She's won over 28 awards since 1986.
She also has many honorary doctorates from 12 different schools.

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